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24 Hour Urgent Care in Cape Girardeau

Cape Girardeau is the county seat of Cape Girardeau County in southeast Missouri along the Mississippi River, serving as the regional healthcare, educational, and retail hub for a large multi-county area. Urgent care centers on Kingshighway and William Street serve Cape Girardeau residents and patients from the broader Bootheel and southeast Missouri region.

Filter clinics:

⚠️Always call ahead to verify hours and availability. Clinic information on this site may be outdated or inaccurate. Do not rely solely on this listing — confirm directly with the clinic before visiting. For medical emergencies, call 911.
ℹ️Insurance & Medicaid: Most urgent care centers accept Medicaid, Medicare, and major PPO/HMO plans. Coverage varies by location — call ahead to confirm your specific plan is accepted before your visit.

AFC Urgent Care – Cape GirardeauOpen Now

Address: 1600 S Mount Auburn Rd, Cape Girardeau, MO 63701
Hours: Mon–Sun 8am–8pm
Insurance accepted: Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Medicare, Medicaid
Without insurance: $100–$175 typical visit (varies by location)
Ages served: All ages
✓ Online check-in✓ Telehealth available
Services:
Urgent careOccupational healthDOT physicalsDrug testingX-rayLab testingTelehealth
Map showing location of AFC Urgent Care – Cape Girardeau

NextCare Urgent Care – Cape GirardeauOpen Now

Address: 3200 William St, Cape Girardeau, MO 63701
Hours: Mon–Sun 8am–8pm
Website: nextcare.com
Insurance accepted: Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Medicare, Medicaid
Without insurance: $100–$200 typical visit; $65 virtual visit; discount program $39/visit
Ages served: All ages
✓ Online check-in✓ Telehealth available
Services:
Urgent carePhysicalsX-rayLab testingTelehealthSports medicine
Map showing location of NextCare Urgent Care – Cape Girardeau

MedExpress Urgent Care – Cape GirardeauOpen Now

Address: 800 S Kingshighway, Cape Girardeau, MO 63701
Hours: Mon–Fri 8am–8pm, Sat–Sun 9am–5pm
Insurance accepted: Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Medicare, Medicaid
✓ Online check-in
Services:
Urgent careEmployer health servicesX-rayLab testing
Map showing location of MedExpress Urgent Care – Cape Girardeau

Concentra Urgent Care – Cape GirardeauOpen Now

Address: 2400 Kingshighway, Cape Girardeau, MO 63701
Hours: Mon–Fri 7am–6pm, Sat 8am–12pm
Website: concentra.com
Insurance accepted: Most major insurance, Workers' comp, Medicare
Ages served: 2 and older
✓ Online check-in
Services:
Occupational healthWorkers' compDOT physicalsDrug & alcohol testingUrgent careX-rayPhysical therapy
Map showing location of Concentra Urgent Care – Cape Girardeau

GoHealth Urgent Care – Cape GirardeauOpen Now

Address: 500 N Kingshighway, Cape Girardeau, MO 63701
Hours: Mon–Sun 8am–8pm
Insurance accepted: Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Medicare, Medicaid
Ages served: All ages
✓ Online check-in✓ Telehealth available
Services:
Urgent careVirtual careX-rayEKGLab testingOccupational health
Map showing location of GoHealth Urgent Care – Cape Girardeau

FastMed Urgent Care – Cape GirardeauOpen Now

Address: 2000 S Mount Auburn Rd, Cape Girardeau, MO 63701
Hours: Mon–Sun 8am–10pm
Website: fastmed.com
Insurance accepted: Aetna, BCBS, Cigna, Humana, Medcost, Medicare, Medicaid, TRICARE
Without insurance: ~$199 base visit (varies by service)
Ages served: All ages
✓ Online check-in✓ Telehealth available
Services:
Urgent careOccupational healthSports physicalsVaccinationsX-rayLab testing
Map showing location of FastMed Urgent Care – Cape Girardeau

Cape Girardeau Urgent Care CenterOpen Now

Address: 3600 William St, Cape Girardeau, MO 63701
Hours: Mon–Sun 9am–9pm
Map showing location of Cape Girardeau Urgent Care Center

Cape Girardeau Walk-In ClinicOpen Now

Address: 1200 S Kingshighway, Cape Girardeau, MO 63701
Hours: Mon–Fri 8am–6pm, Sat–Sun 9am–4pm
Map showing location of Cape Girardeau Walk-In Clinic

Cape Girardeau Immediate CareOpen Now

Address: 2800 Kingshighway, Cape Girardeau, MO 63701
Hours: Mon–Sun 8am–8pm
Map showing location of Cape Girardeau Immediate Care

Cape Girardeau Medical Walk-InOpen Now

Address: 900 N Kingshighway, Cape Girardeau, MO 63701
Hours: Mon–Fri 8am–7pm, Sat–Sun 9am–5pm
Map showing location of Cape Girardeau Medical Walk-In

What to Expect at Urgent Care in Cape Girardeau

Typical Cost
$100–$200
Without insurance for a basic exam. X-rays, labs, or stitches add to the total. Many clinics post self-pay rates online.
Average Wait
15–45 min
Weekday mornings tend to be the shortest. Use online check-in where available to hold your spot before you arrive.
What to Bring
ID & Insurance Card
Photo ID, insurance card, and a list of current medications and known allergies. Most clinics also accept walk-ins without prior paperwork.
When to Go to the ER
Chest pain, stroke signs, or major trauma
Urgent care is for non-life-threatening conditions only. For emergencies, call 911 or go directly to the nearest emergency room.

Urgent Care in Cape Girardeau — Frequently Asked Questions

Is urgent care open on weekends in Cape Girardeau?

Yes — most urgent care centers in Cape Girardeau are open on Saturdays and Sundays, typically from 8am to 8pm. Some locations have reduced Sunday hours, so check the listings above for exact weekend hours at each clinic.

Do I need an appointment for urgent care in Cape Girardeau?

No appointment is needed at most Cape Girardeau urgent care centers. Walk-ins are welcome at all locations listed above. Some clinics offer online check-in so you can hold your spot before you arrive and reduce your wait time.

How much does urgent care cost in Cape Girardeau?

A typical urgent care visit in Cape Girardeau costs between $100 and $200 without insurance for a basic exam. Additional services such as X-rays, lab tests, or stitches will increase the total. Most clinics will provide a cost estimate when you call, and many post self-pay rates on their website.

Does urgent care in Cape Girardeau accept Medicaid?

Yes — most urgent care centers in Cape Girardeau accept Medicaid along with Medicare and major commercial insurance plans. Federal law requires Medicaid to cover urgent care for emergency and necessary medical conditions. Call the clinic ahead to confirm your specific Medicaid plan is accepted and that the location is in-network before your visit.

Does urgent care in Cape Girardeau accept insurance?

Most urgent care centers in Cape Girardeau accept major insurance plans including commercial insurance, Medicare, and Medicaid. Coverage and copays vary by plan and location, so call ahead to confirm your insurance is accepted before your visit.

What is the wait time at urgent care in Cape Girardeau?

Average wait times at Cape Girardeau urgent care centers are typically 15 to 45 minutes, though this varies by location and time of day. Early morning visits and weekday mornings tend to have the shortest waits. Using online check-in where available can also reduce your time in the waiting room.

What can urgent care treat in Cape Girardeau?

Cape Girardeau urgent care centers treat a wide range of non-life-threatening conditions including colds, flu, infections, minor injuries, rashes, UTIs, and more. Many locations also provide X-rays, lab work, and vaccinations. For chest pain, difficulty breathing, or other emergencies, go to the nearest ER or call 911.

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