Urgent Care Open Now in Sioux Falls, SD
Sioux Falls urgent care centers serve South Dakota's largest city and the economic capital of the Northern Plains, anchored by Sanford Health and Avera Health — two of the nation's largest rural health systems — with walk-in clinics along South Louise Avenue, West 41st Street, and East 10th Street. The city's remarkable population growth, financial services and healthcare employment anchors, and role as the regional medical destination for patients from across South Dakota, southern Minnesota, and northwestern Iowa create strong urgent care demand in a fast-growing market where new residential development consistently outpaces primary care availability.
Filter clinics:
⚠️Always call ahead to verify hours and availability. Clinic information on this site may be outdated or inaccurate. Do not rely solely on this listing — confirm directly with the clinic before visiting. For medical emergencies, call 911.
ℹ️Insurance: Most urgent care centers accept major PPO/HMO plans, Medicare, and Medicaid. Coverage varies — call the clinic directly to confirm your plan is accepted before your visit.
Sanford Urgent Care – West 41st St
Address: 4300 W 41st St, Sioux Falls, SD 57106
Phone: (605) 333-6000
Hours: Mon–Fri 8am–8pm, Sat–Sun 9am–5pm
Website: sanfordhealth.org
Avera Walk-In Clinic – Louise Ave
Address: 3808 S Louise Ave, Sioux Falls, SD 57106
Phone: (605) 322-7000
Hours: Mon–Fri 8am–8pm, Sat–Sun 9am–5pm
Website: locations.avera.org
AFC Urgent Care – Sioux Falls
Address: 2301 E 10th St, Sioux Falls, SD 57103
Phone: (605) 275-2273
Hours: Mon–Fri 8am–8pm, Sat–Sun 9am–5pm
Website: locations.avera.org
Insurance accepted: Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Medicare, Medicaid
Without insurance: $100–$175 typical visit (varies by location)
Ages served: All ages
✓ Online check-in✓ Telehealth available
Services:
Urgent careOccupational healthDOT physicalsDrug testingX-rayLab testingTelehealth
Concentra Urgent Care – Sioux Falls
Address: 300 S Sycamore Ave, Sioux Falls, SD 57110
Phone: (605) 339-9800
Hours: Mon–Fri 7am–6pm, Sat 8am–12pm
Website: sfsh.com
Insurance accepted: Most major insurance, Workers' comp, Medicare
Ages served: 2 and older
✓ Online check-in
Services:
Occupational healthWorkers' compDOT physicalsDrug & alcohol testingUrgent careX-rayPhysical therapy
MedExpress Urgent Care – 41st St
Address: 3900 W 41st St, Sioux Falls, SD 57106
Phone: (605) 361-7700
Hours: Mon–Fri 8am–8pm, Sat–Sun 9am–5pm
Website: eyemartexpress.com
Insurance accepted: Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Medicare, Medicaid
Services:
Urgent careEmployer health servicesX-rayLab testing
FastMed Urgent Care – Sioux Falls
Address: 3216 S Minnesota Ave, Sioux Falls, SD 57105
Phone: (605) 334-6100
Hours: Mon–Sun 8am–8pm
Website: sfsh.com
Insurance accepted: Aetna, BCBS, Cigna, Humana, Medcost, Medicare, Medicaid, TRICARE
Without insurance: ~$199 base visit (varies by service)
Ages served: All ages
✓ Online check-in✓ Telehealth available
Services:
Urgent careOccupational healthSports physicalsVaccinationsX-rayLab testing
Sanford Walk-In – East 10th St
Address: 1500 E 10th St, Sioux Falls, SD 57103
Phone: (605) 333-6100
Hours: Mon–Fri 8am–8pm, Sat–Sun 9am–5pm
Website: sanfordhealth.org
NextCare Urgent Care – Sioux Falls
Address: 5400 S Cliff Ave, Sioux Falls, SD 57108
Phone: (605) 361-4400
Hours: Mon–Fri 8am–8pm, Sat–Sun 9am–5pm
Website: sfsh.com
Insurance accepted: Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Medicare, Medicaid
Without insurance: $100–$200 typical visit; $65 virtual visit; discount program $39/visit
Ages served: All ages
✓ Online check-in✓ Telehealth available
Services:
Urgent carePhysicalsX-rayLab testingTelehealthSports medicine
Avera Medical Group – Walk-In
Address: 1000 E 23rd St, Sioux Falls, SD 57105
Phone: (605) 322-5500
Hours: Mon–Sun 8am–8pm
Website: locations.avera.org
GoHealth Urgent Care – Sioux Falls South
Address: 6401 S Minnesota Ave, Sioux Falls, SD 57108
Phone: (605) 361-8800
Hours: Mon–Fri 8am–8pm, Sat–Sun 9am–5pm
Website: sfsh.com
Insurance accepted: Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Medicare, Medicaid
Ages served: All ages
✓ Online check-in✓ Telehealth available
Services:
Urgent careVirtual careX-rayEKGLab testingOccupational health
What to Expect at Urgent Care in Sioux Falls, SD
Typical Cost
$100–$200
Without insurance for a basic exam. X-rays, labs, or stitches add to the total. Many clinics post self-pay rates online.
Average Wait
15–45 min
Weekday mornings tend to be the shortest. Use online check-in where available to hold your spot before you arrive.
What to Bring
ID & Insurance Card
Photo ID, insurance card, and a list of current medications and known allergies. Most clinics also accept walk-ins without prior paperwork.
When to Go to the ER
Chest pain, stroke signs, or major trauma
Urgent care is for non-life-threatening conditions only. For emergencies, call 911 or go directly to the nearest emergency room.
Urgent Care in Sioux Falls, SD — Frequently Asked Questions
Is urgent care open on weekends in Sioux Falls, SD?
Yes — most urgent care centers in Sioux Falls, SD are open on Saturdays and Sundays, typically from 8am to 8pm. Some locations have reduced Sunday hours, so check the listings above for exact weekend hours at each clinic.
Do I need an appointment for urgent care in Sioux Falls, SD?
No appointment is needed at most Sioux Falls, SD urgent care centers. Walk-ins are welcome at all locations listed above. Some clinics offer online check-in so you can hold your spot before you arrive and reduce your wait time.
How much does urgent care cost in Sioux Falls, SD?
A typical urgent care visit in Sioux Falls, SD costs between $100 and $200 without insurance for a basic exam. Additional services such as X-rays, lab tests, or stitches will increase the total. Most clinics will provide a cost estimate when you call, and many post self-pay rates on their website.
Does urgent care in Sioux Falls, SD accept insurance?
Most urgent care centers in Sioux Falls, SD accept major insurance plans including commercial insurance, Medicare, and Medicaid. Coverage and copays vary by plan and location, so call ahead to confirm your insurance is accepted before your visit.
What is the wait time at urgent care in Sioux Falls, SD?
Average wait times at Sioux Falls, SD urgent care centers are typically 15 to 45 minutes, though this varies by location and time of day. Early morning visits and weekday mornings tend to have the shortest waits. Using online check-in where available can also reduce your time in the waiting room.
What can urgent care treat in Sioux Falls, SD?
Sioux Falls, SD urgent care centers treat a wide range of non-life-threatening conditions including colds, flu, infections, minor injuries, rashes, UTIs, and more. Many locations also provide X-rays, lab work, and vaccinations. For chest pain, difficulty breathing, or other emergencies, go to the nearest ER or call 911.
Urgent Care Guides & Resources
ER vs. Urgent Care — Which Should You Choose?How Much Does Urgent Care Cost?Walk-In vs. Appointment — What to KnowUrgent Care for Flu & ColdUrgent Care for Strep ThroatUrgent Care for UTIsUrgent Care for Pink EyeUrgent Care for Ear InfectionsUrgent Care for Cuts & StitchesUrgent Care for Sprained AnklesUrgent Care for Fever in ChildrenDOT Physicals at Urgent CareSTD Testing at Urgent CareIV Hydration TherapyPediatric Urgent Care for KidsSports Injury & Orthopedic CareOccupational Health & Drug Testing
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